In 2015, a clinical study was carried out to evaluate the effect of a 50 mg supplementation of SENACTIV® on the production of ATP in 14 cyclists with an average age of 21 years. This study was conducted double-blind, with one group receiving SENACTIV® and one group receiving a placebo.
The cyclists took 50 mg of SENACTIV® at two different times: 12 hours and 1 hour before intense physical exertion. The results of the study revealed a significant increase of 47% in the activity of citrate synthase , which is the first enzyme in the Krebs cycle*. This indicates that citric acid plays a vital role in the production of ATP, which is the energy needed for proper cell function.
*The Krebs cycle, also known as the citric acid cycle, is a crucial metabolic process that actively participates in the production of cellular energy. Indeed, a complete turn of the Krebs cycle makes it possible to obtain 12 molecules of ATP, thus demonstrating its importance in the production of energy necessary to support cellular activities.
Study Hou, C.-W., Lee, S.-D., Kao, C.-L., Cheng, I.-S., Lin, Y.-N., Chuang, S.-J., … Kuo, C.-H. (2015). Improved Inflammatory Balance of Human Skeletal Muscle during Exercise after Supplementations of the Ginseng-Based Steroid Rg1. Plos One, 10(1). doi: 10.1371/journal.pone.0116387