Astragin® has a positive effect on the microbiota and the immune system. In vivo studies in rats have demonstrated that Astragin® contributes to the repair of damaged epithelial cells and the reduction of inflammation in the lamina propria, a membrane that lines the body's cavities and contains numerous cells. immune, such as:
- gut-associated lymphoid tissue (GALT)
- T cells
- plasma cells
- mast cells
- dendritic cells
These results indicate that Astragin® plays a crucial role in maintaining intestinal health and the overall immune system, supporting the balance of the immune response and promoting better resistance against external attacks.*
A second study was carried out, the astragalosides present in Astragalus membranaceus were observed to have beneficial effects on the immune system by:
Activating and strengthening T lymphocytes and B lymphocytes , the cellular components of the adaptive immune system,
- Inducing the production of IFN-γ and the activity of IL-2 , two cytokines essential for the immune response,
- Promoting the engagement of T helper cells.**
The third study was carried out on ginsenoside Rg1. It is a major active ingredient in Panax notoginseng , which has shown an effect on the immune system by:
- Increasing the activity of T lymphocytes and stimulating B lymphocytes in the production of antibodies,
- Acting as an immune modulator of B cell activation in autoimmune diseases.***
*Study “AstraGin Immune Health WP e250221.pdf”.
**Study Y. Qi, F. Gao, L. Hou, and C. Wan, “Anti-Inflammatory and Immunostimulatory Activities of Astragalosides”, Am. J. Chin. Med. , Sep 2017, doi: 10.1142/S0192415X1750063X.
*** Study M. Riaz, NU Rahman, M. Zia-Ul-Haq, HZE Jaffar, and R. Manea, “Ginseng: A dietary supplement as immune-modulator in various diseases,” Trends Food Sci. Technol., vol. 83, p. 12‑30, Jan. 2019, doi: 10.1016/j.tifs.2018.11.008.